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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
20
Human Site:
S72
Identified Species:
27.5
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S72
K
S
N
T
E
P
Q
S
P
P
I
A
S
P
K
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S72
K
S
N
T
E
P
Q
S
P
P
I
A
S
P
K
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
S72
K
S
N
T
E
P
Q
S
P
P
I
A
S
P
K
Dog
Lupus familis
XP_533766
1089
122761
S72
K
S
N
T
E
P
Q
S
Q
P
V
A
S
P
K
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
Q72
N
S
T
S
S
E
P
Q
S
P
P
T
A
S
Q
Rat
Rattus norvegicus
NP_446123
1093
121882
S72
N
S
S
S
E
P
Q
S
S
P
T
A
S
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
S72
N
S
N
P
E
P
Q
S
Q
P
V
A
S
P
K
Chicken
Gallus gallus
O42184
1433
161009
Q76
G
N
K
P
G
F
I
Q
F
L
G
E
T
Q
F
Frog
Xenopus laevis
Q5PQ23
649
75475
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
P72
E
E
Q
T
T
S
P
P
P
S
S
E
A
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
A24
I
Q
D
D
D
S
K
A
A
E
K
D
S
P
M
Honey Bee
Apis mellifera
XP_394037
1326
150590
H99
P
K
F
N
E
M
D
H
N
A
K
A
N
A
L
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
F654
K
K
G
K
S
G
S
F
M
T
V
S
M
L
Y
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
L72
A
G
S
L
S
G
K
L
Q
S
N
S
E
E
D
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
E67
S
F
M
G
N
K
S
E
D
S
T
D
E
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
A48
D
D
K
S
D
S
A
A
E
D
A
A
S
S
M
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
86.6
N.A.
13.3
53.3
N.A.
73.3
0
0
13.3
N.A.
13.3
13.3
6.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
66.6
N.A.
80
13.3
0
26.6
N.A.
40
20
20
20
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
0
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
0
6
12
6
6
6
48
12
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
6
6
12
0
6
0
6
6
0
12
0
0
6
% D
% Glu:
6
6
0
0
42
6
0
6
6
6
0
12
12
6
0
% E
% Phe:
0
6
6
0
0
6
0
6
6
0
0
0
0
0
6
% F
% Gly:
6
6
6
6
6
12
0
0
0
0
6
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
6
0
0
0
0
0
6
0
0
0
18
0
0
6
0
% I
% Lys:
30
12
12
6
0
6
12
0
0
0
12
0
0
0
30
% K
% Leu:
0
0
0
6
0
0
0
6
0
6
0
0
0
6
6
% L
% Met:
0
0
6
0
0
6
0
0
6
0
0
0
6
0
12
% M
% Asn:
18
6
30
6
6
0
0
0
6
0
6
0
6
0
0
% N
% Pro:
6
0
0
12
0
36
12
6
24
42
6
0
0
36
0
% P
% Gln:
0
6
6
0
0
0
36
12
18
0
0
0
0
12
6
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
6
42
12
18
18
18
12
36
12
18
6
12
48
18
6
% S
% Thr:
0
0
6
30
6
0
0
0
0
6
12
6
6
0
6
% T
% Val:
0
0
0
0
0
0
0
0
0
0
18
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _